The hydrophobic impact exists as a driving force in thermodynamics only if there's the presence of an aqueous medium with an amphiphilic molecule containing a large hydrophobic region. The hydrophobic impact (Figure 2. In case you loved this information and you would want to receive details about accobio.com i implore you to visit our own web-site. 37) is the phenomenon through which the hydrophobic chains of a protein collapse into the core of the protein (away from the hydrophilic setting).