HepG2 (A) and Pro-5 (B) cells were transduced with a constant amount of AAV1-luc or AAV6-luc vectors in the presence of a 200-fold-excess amount of competing AAV1, AAV6, or AAV2 encapsidated λ phage DNA-containing vector at 37°C for 1 h. However, more and more studies suggest that AAV2-based vectors are rate limiting in certain tissues (5, 32). If you enjoyed this write-up and you would certainly like to obtain more info concerning Supplier of sialic acid powder for drink Ingredients kindly browse through the website. The availability of other AAV serotypes with tissue preference for transduction, such as AAV1 and AAV6 for muscle (2, 5) and AAV8 for liver (12, 14, 25), has overcome this restriction.