Specificity of carbohydrate binding by AAV1 capsids on a glycan array. Interestingly, an older version of the array, containing glycans immobilized as biotinylated glycosides on a 384-well streptavidin-coated plate, was used to screen the sugar binding specificity of the parvovirus minute virus of mice (MVM) capsids (M. This array, containing sialylated and nonsialylated sugars with different linkages and modifications, was constructed for identifying specific carbohydrate binding partners for proteins. Should you have virtually any concerns concerning wherever and the way to utilize sialic acid manufacturers, you possibly can call us with our web site. In addition, through the CFG, we were able to test AAV1 on a unique glycan array and demonstrate specific binding to glycans containing terminal sialic acids attached α2,3 and α2,6 to the Galβ1-4GlcNAc motif (Fig. (Fig.
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