Neuraminidases and other reagents were obtained from Sigma-Aldrich. If you adored this article and you would like to obtain even more details relating to manufacturer of sialic acid powder for pharmaceutical Ingredients kindly go to our site. To determine whether sialic acids play a role in endothelial barrier function, cells were treated with neuraminidases to hydrolyze sialic acid moieties. Two components of glycocalyx structure that may play a role in determining function in glycoproteins are 1) the terminal sugar residue(s) on the oligosaccharide chain(s) and 2) the amino acid residue attachment site (N- vs.
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