This was followed by the addition of neuraminidase solution or buffer control to each well and continued resistance measurement 4 (or more) h. If you loved this short article and you would certainly like to receive more details relating to manufacturer of sialic acid powder as Raw Material for Supplements kindly visit our web page. AAV6 relies more on sialic acid or sialic acid-containing glycoproteins than AAV1 for cell entry and/or subsequent steps of infection. Neuraminidases are enzymes that cleave via hydrolysis α(2-3)-, α(2-6)-, and α(2-8)-linked terminal sialic acid residues bound to Gal, GlcNac, GalNAc, AcNeu, or GlyNeu residues of oligosaccharides, glycolipids, and glycoproteins (17). Neuraminidases from different sources exhibit different specificities for sialic acid linkages hydrolyzed (4, 24).