Mucin competition was carried out by pretreating rAAV with bovine submandibular gland mucin (Sigma) for 30 min at 20°C. In the event you liked this informative article along with you wish to get guidance regarding Supplier of sialic acid powder for beverage Ingredients generously visit our own internet site. AAV vectors, in the presence or absence of mucin, ...
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Specificity of carbohydrate binding by AAV1 capsids on a glycan array. Interestingly, an older version of the array, containing glycans immobilized as biotinylated glycosides on a 384-well streptavidin-coated plate, was used to screen the sugar binding specificity of the parvovirus minute virus of mice (MVM) capsids (M. This array, containing sialylated and ...
Preliminary studies have demonstrated structural differences in the glycocalyx of pulmonary artery endothelial cells compared with pulmonary microvascular endothelial cells. In addition, if the interaction between sialic acid and the AAV6 capsid is more efficient than that of AAV1 for cell entry, this might account for the increased transduction of AAV6 comp...