In 2006, the European Food Safety Authority acknowledged that the SSC opinion was confirmed, that the BSE threat of bone-derived gelatin was small, and that it really helpful removal of the 2003 request to exclude the skull, amino acids manufacturer for supplements brain, and vertebrae of bovine origin older than 12 months from the material utilized in gelatin manufacturing. Food and Drug Administration (FDA), with assist from the TSE (transmissible spongiform encephalopathy) Advisory Committee, started monitoring the potential threat of transmitting animal diseases, particularly bovine spongiform encephalopathy (BSE), commonly often called mad cow illness.