This was followed by the addition of neuraminidase solution or buffer control to each well and continued resistance measurement 4 (or more) h. AAV6 relies more on sialic acid or sialic acid-containing glycoproteins than AAV1 for cell entry and/or subsequent steps of infection. If you adored this article so you would like to get more info about sialic acid powder supplier nicely visit the web site. Neuraminidases are enzymes that cleave via hydrolysis α(2-3)-, α(2-6)-, and α(2-8)-linked terminal sialic acid residues bound to Gal, GlcNac, GalNAc, AcNeu, or GlyNeu residues of oligosaccharides, glycolipids, and glycoproteins (17). Neuraminidases from different sources exhibit different specificities for sialic acid linkages hydrolyzed (4, 24). The lectin from Arachis hypogaea binds to the sequence Gal(β1,3)GalNAc, also known as T-antigen (19, 24).
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