In 2006, the European Food Safety Authority acknowledged that the SSC opinion was confirmed, that the BSE threat of bone-derived gelatin was small, and that it advisable removal of the 2003 request to exclude the skull, custom amino acids manufacturer brain, and vertebrae of bovine origin older than 12 months from the material utilized in gelatin manufacturing. Food and Drug Administration (FDA), with help from the TSE (transmissible spongiform encephalopathy) Advisory Committee, started monitoring the potential danger of transmitting animal diseases, especially bovine spongiform encephalopathy (BSE), generally generally known as mad cow disease.
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