This was followed by the addition of neuraminidase solution or buffer control to each well and continued resistance measurement 4 (or more) h. AAV6 relies more on sialic acid or sialic acid-containing glycoproteins than AAV1 for cell entry and/or subsequent steps of infection. Neuraminidases are enzymes that cleave via hydrolysis α(2-3)-, α(2-6)-, and α(2-8)-linked terminal sialic acid residues bound to Gal, GlcNac, GalNAc, AcNeu, or GlyNeu residues of oligosaccharides, glycolipids, and glycoproteins (17). Neuraminidases from different sources exhibit different specificities for sialic acid linkages hydrolyzed (4, 24) Should you loved this short article and you would want to receive more information concerning sialic acid powder suppliers kindly visit our web-site. .