Cigarette do not convert nicotine to NNK attributable to their lower operating temperatures. Causes for hesitancy embody challenges making certain that quality control measures on the gadgets and liquids are met, vapewait unknown second hand vapingready vapour inhalation results, uncertainty about EC use resulting in the initiation of smoking or results on people new to smoking who develop nicotine dependence, vapingready unknown long-time period effects of electronic cigarette use on human health, vapingready uncertainty about the effects of ECs on smoking laws and vaporeach smoke free legislation measures, vaporneed and uncertainty about involvement of the tobacco business.
Traditional e-cigarettes use free-based mostly nicotine liquids, vapepretty whereas pod mods use nicotine salts which give them a bigger dose of nicotine per inhalation. Studies showed that with a one hundred mg/kg dose of NNK, vapefollow several point mutations were formed in the RAR-β gene, inducing tumorigenesis in the lungs.