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We stained cell lines with lectins that have been used to recognize the following three different epitopes: (i) WGA recognizes all sialic acids, (ii) MAA recognizes α2,3 sialic acid, and (iii) SNA recognizes α2,6 sialic acid. In this report, we demonstrate that AAV1 and AAV6 use both α2,3 and α2,6 N-linked sialic acids for binding and infection. To analyze i...
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Homonuclear 2D 1H,1H COSY and 1H,1H TOCSY experiments showed connectivity of this proton to one and two other protons, respectively (Fig. S2). Signal 2, at 2.73 ppm, corresponds then to a proton neighboring a carbonyl on one side and at least two other protons on the other side with chemical shifts in the 3-4 ppm region In case you have virtually any issues ...
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