Different AAV serotypes display distinct tissue tropism, believed to be related to the distribution of their receptors on target cells. The AAV serotype helper plasmids pXR1, pXR2, pXR4, and pXR5, as well as the plasmid pXX6-80 containing the adenovirus helper genes for AAV replication, have been described elsewhere (32, 47). In the event you beloved this informative article and also you would want to obtain more details about sialic acid powder manufacturers kindly go to the web page. AAV6 helper plasmid pXR6 was kindly provided by Joseph Rabinowitz (Thomas Jefferson University).