The data from these assays were complemented by a glycan array analysis which determined that AAV1 efficiently binds to NeuAcα2-3GalNAcβ1-4GlcNAc as well as glycoproteins containing NeuAcα2-3/α2-6Galβ1-4GlcNAc N-linked glycans. Sialic acids are typically found as terminal monosaccharides of glycans carried by cell surface glycoproteins. When you adored this short article as well as you desire to receive guidance relating to manufacturer of sialic acid powder for Supplement Ingredients i implore you to pay a visit to the web-site. Mucin competition was carried out by pretreating rAAV with bovine submandibular gland mucin (Sigma) for 30 min at 20°C.