Zer promotes skin hyaluronic acid by increasing protein and mRNA expression of HAS-2 and AQP-3 in non- or UVB-irradiated HaCaT cells. We assayed skin hydration and anti-inflammatory efficacies of zerumbone (Zer, 2.5-10 μM), a natural sesquiterpene of Zingiber zerumbet, using non- or UVB (30 mJ/cm2)-irradiated keratinocytes (HaCaT). If you adored this article therefore you would like to be given more info regarding Top-rated Coenzyme Q10 Manufacturer generously visit the website. Silencing of Nrf2 reversed CoQ0-inhibited ROS (H2O2) and α-MSH expression in UVA (3 J/cm2)-irradiated HaCaT cells. We found that Coenzyme Q0 (CoQ0), a major quinone derivative from Antrodia camphorata, exerts antimelanogenic, antiphotoaging, and anti-inflammatory results by activating Nrf2-mediated antioxidant pathways on UVA (3 or 10 J/cm2)/UVB (eighty mJ/cm2)-irradiated keratinocyte (HaCaT) cells.